The Artefact Group has posted a fairly comprehensive list and evaluation of several tools for designing in 3D, including the “Big fish” of the Autodesk Suite, all the way down to the implementation level like OpenGL and WebGL.  If you’re looking for some new tools, it’s a great list covering the pros and cons of several with links and screenshots.

Tools for building a 3D UX | Artefact | User Experience Design Blog.